19 of Medvedev's 21 titles have been achieved on hardcourt
A revitalized the Russian player secured his maiden trophy for 882 days with a win over Frenchman Moutet in the competition final.
Medvedev, a former world number one, has had a torrid season, winning just a single victory at the major tournaments and experiencing a setback at the US Open.
His unpredictability on the tennis tour - and struggles with his serving in specific - resulted in him falling of the world's top 10 and ultimately separating with long-time trainer his previous coach.
Now working with his coach and his other coach, he has consistently advanced in the past month - peaking in a tightly fought three-set triumph over Frenchman Corentin Moutet.
This marks his initial title after the Italian tournament and first on a hard court after that period of that year.
The win also signifies he has achieved twenty-one victories at twenty-one distinct competitions.
"This marks the first occasion I have attended a tournament with my two daughters simultaneously, so to get a championship is especially meaningful," stated ranked player Daniil Medvedev.
"This title is in dedication of my child her name, because the initial championship I got when my older daughter my daughter was delivered was for her."
The tennis star, the 2021 US Open champion, had failed in his past six finals, including in the German tournament previously this season.
His defensive approach and frequent emotional displays on the tennis court had led observers to doubt if his skill to perform at the highest level was finished.
However the athlete has altered his approach in the past month, striving to advance forward and perform positively, reinforced by an better serving game.
Medvedev fought back from a disadvantage in the first set against the difficult Frenchman, winning 4 of the concluding five points to gain the advantage.
Both players swapped service breaks in the second set before the challenger, striving for his first professional championship, gained dominance to force a third set.
He rescued 4 early-game break points in a tight final set before Medvedev won the break to 15 to secure the win.
Fittingly, the winner secured the title with a rally at the net area, with the Frenchman incapable to control a volley after two hours and 38 minutes.